SFRP Family and Cardiac Development

JINYa-Qiong,JIAZhu-Qing,ZHOUChun-Yan

Chinese Journal of Biochemistry and Molecular Biology ›› 2008, Vol. 24 ›› Issue (12) : 1103-1108.

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Chinese Journal of Biochemistry and Molecular Biology ›› 2008, Vol. 24 ›› Issue (12) : 1103-1108.
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SFRP Family and Cardiac Development

  • JIN Ya-Qiong, JIA Zhu-Qing, ZHOU Chun-Yan
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Abstract

The Wnt pathways play crucial roles in cardiac development. The SFRP (secreted frizzledrelated protein) family, as a class of important Wnt signal regulators, has received increasing attentions for its roles in cardiac development and cardiomyocyte differentiation. Recent researches have discovered that SFRP appeared to have more complicated regulatory functions on Wnt signal transduction than just being a negative regulator. In this review, we will focus on the discussions of SFRP functions and the Wnt signaling during cardiac development.

Key words

secreted frizzledrelated protein (SFRP) / Wnt / cardiac development

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JINYa-Qiong,JIAZhu-Qing,ZHOUChun-Yan. SFRP Family and Cardiac Development[J]. Chinese Journal of Biochemistry and Molecular Biology, 2008, 24(12): 1103-1108

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