Synthesis and Proteolysis of Gly-L-His-L-Lys(GHK)

PENG Xiao san, CHEN Jun hui , ZHANG Xin, ZHANG Dong mei, WANG Xin chang

Chinese Journal of Biochemistry and Molecular Biology ›› 2003, Vol. 19 ›› Issue (03) : 406-409.

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Chinese Journal of Biochemistry and Molecular Biology ›› 2003, Vol. 19 ›› Issue (03) : 406-409.
Article

Synthesis and Proteolysis of Gly-L-His-L-Lys(GHK)

  • PENG Xiao san, CHEN Jun hui , ZHANG Xin, ZHANG Dong mei, WANG Xin chang
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Abstract

Gly\| L His L Lys(GHK) was synthesized by liquid\|phase method. The HPLC analysis indicated that the proteolysis of GHK was initiated at the N terminal in liver homogenate. The result suggested that GHK was rapidly degraded by aminopeptidases in liver.

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PENG Xiao san, CHEN Jun hui , ZHANG Xin, ZHANG Dong mei, WANG Xin chang. Synthesis and Proteolysis of Gly-L-His-L-Lys(GHK)[J]. Chinese Journal of Biochemistry and Molecular Biology, 2003, 19(03): 406-409

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