本文报告了乳腺癌标本中N-ras、c-myc和neu癌基因异常改变,包括扩增和重排,并对这些结构改变与乳腺癌临床指征的关系作了初步的分析。本文的实验结果表明这些癌基因可能在人类乳腺癌的生物学行为和发病方面起着一定的作用。
Abstract
Some alterations, including amplification and rearrangement, of oncogene N-ras, c-myc and neu in breast cancer were reported. These structural changes were correlated to some extent with several disease parameters.Our results indicate that t-hese oncogenes may play some roles in the biologic behavior and pathogenesis of human breast cancer.
关键词
乳腺癌 /
癌基因 /
分子杂交 /
扩增 /
重排
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Key words
Breast cancer /
Oncogene /
Molecular Hybridization /
Amplification /
Rearrangement
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参考文献
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脚注
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