本文进一步研究了我国不同民族的正常个体以及β地中海贫血患者θ珠蛋白基因5′侧序列中的多态性HincⅡ位点及其遗传性质。在广西壮族正常个体和β地中海贫血纯合子中,该多态性位点的发生频率均为75％,与正常汉族人测得值相近。家系分析资料表明,该多态性位点完全按照孟德尔规律进行遗传。

Further studies on HincⅡ polymorphic restriction site 5' to e globin gene of human DNAs from normai Zhuan individuals members of Han families and β-thalassemia patients have been carried out by restriction enzyme analysis. The frequency of the HincⅡ site polymorphism among Zhuan people and β-thalassemia patients were found to be 75%,Which was rather close to that previously reported among Han people. Results from family study showed that the inheritance of the polymorphic site among family members seemed to follow Mendel's rule.