����
����Ŀ¼ | ����Ŀ¼ | ����� | ������
<<
[an error occurred while processing this directive]
|
[an error occurred while processing this directive]
>>
ֲ��Rubisco�������ĵ�ģ�����
����Ȼ *
@����Ȼ$�人��ѧ�����ѧѧԺ!�����人430072
@��ε÷$�人��ѧ�����ѧѧԺ!�����人430072
@��ʤ��$�人��ѧ�����ѧѧԺ!�����人430072
@������$�人��ѧ�����ѧѧԺ!�����人430072
@������$�人��ѧ�����ѧѧԺ!�����人430072
@���$�人��ѧ�����ѧѧԺ!�����人430072
Simulation on Botanic Rubisco Active Center
XIONG Xiao ran, CHEN Wei mei *, FENG Sheng yan, GUO Ming xiong, AI Jian yu, WU Bin (School of Life Sciences, Wuhan University, Wuhan 430072, China)
Download: PDF (339KB)
HTML 0KB
Export: BibTeX or EndNote (RIS)
Supporting Info
ժҪ ͨ����벻ͬ����ϵ�ֲ��Rubisco������ṹ���ص��ȽϷ��� ,����Rubisco�Ļ��Բ�����������һ��Loop6����������ɵ� ;����������������ĵĽ�ϻ���ɻ������ľ�Ĺ���仯 .��һ����SwissPDBViewer���ģ�ⲻͬ����ֲ��Rubisco�����������Loop������������ .������ ,�� 3��Lys�л�Lys2 0 1��Lys334��Lys175��Rubisco�Ƿ��ڻ���״̬������� ,��Щ�л�Ľṹ�仯�Է�����ƿ�������Ҫ�IJο���ֵ
�ؼ�� ��
Rubisco
��������
����
Abstract ��
Through superposition of Rubisco combined with different ligands, it was found that loop6 in the C domain led to a difference between activated Rubisco and non activated one and that the metal ion binding induced a large structural change in active center. The positional relation and hydrogen bond interaction between the residues in active site and this loop region of Rubisco combined with different ligands were simulated through SwissPDBViewer. The results showed that three Lys residues����Lys201, Lys334 and Lys175, were related to the activity of Rubisco. The structural changes in these residues will give instruction to molecular design.
Keywords ��
Rubisco
active center
simulation
Received 2002-09-24;
[1] CurmiPMG ,CascioD ,SweetRM ,EisenbergD ,SchreuderH .����Crystalstructureoftheunactivatedformofribulose1,5 bisphosphatecarboxylase oxygenasefromtobaccorefinedat2.0 resolution.JBiolChem,1992,267(24):16980��16989 [2] KitanoK ,MaedaN ,FukuiT ,AtomiH ,ImanakaT ,MikiK .Crystalstructureofanovel typearchaealRubiscowithpentagonalsymmetry[J].Structure.2001,9:473-481 [3] SchneiderG ,LindqvistY .Crystallographicrefinementandstructureofribulose1,5 bisphosphatecarboxylasefromRhodospirillumrubrumat1.7 resolution?JMolBiol,1990,211:989��1007 [4] ����Ȼ,������,���Ի�,��ʤ��,��ε÷,������,���.���Ӱ���GroEϵͳ������нṹ�빦�ܹ�ϵ�о�.�人��ѧѧ��(��ѧ��)(XiongXiao ran,AiJian yu,WuXian hai,FengSheng yan,ChenWei mei,GuoMing xiong,WuBin.ResearchontherelationofstructureandfunctionofmolecularchaperoneGroE .JWuhanUniv(NatScied)),2002,48(6):741��746 [5] TaylorTC ,FothergillMD ,AnderssonI.Acommonstructuralbasisfortheinhibitionofribulose1,5 bisphosphatecarboxylaseby4 carboxyarabinitol1,5 bisphosphateandxylulose bisphosphate.JBiolChem,1996,271(51):32894��32899 [6] TaylorTC ,AnderssonI .ThestructureofthecomplexbetweenRubiscoanditsnaturalsubstrateribulose1,5 bisphosphat.JMolBiol,1997,265:432��444 [7] AnderssonI.Largestructuresathighresolution:the1.6 crystalstructureofspinachribulose1,5 bisphosphatecarboxylase oxygenasecomplexedwith2 carboxyarabinitolbisphosphate.JMolBiol,1996,259:160��174 [8] LundqvistT ,SchneiderG .Crystalstructureofactivatedribulose1,5 bisphosphatecarboxylasecomplexedwithitssubstrate,ribulose1,5 bisphosphate.JBiolChem,1991,266(19):12604��12611 [9] SoderlindE ,SchneiderG ,GutteridgeS .SubstitutionofASP193toASNattheactivesiteofribulose1,5 bisphosphatecarboxylaseresultsinconformationalchanges.EurJBiochem,1992,206:729��735 [10] GuexN ,PeitschMC .SWISS MODELandtheSwissPdbViewer:anenvironmentforcomparativeproteinmodeling[J].Electrophoresis.1997,18(15):2714-2723 [11] �����Ի�,������,��ʤ��,��ε÷,������,���,����Ȼ.�鵶����A �Ǹ������ģ�����.�人ֲ���о�(WuXian hui,GuoMing xiong,FengSheng yan,ChenWei mei,AiJian yu,WuBin,XiongXiao ran.SimulationanalysisofconcanavalinA carbohydratecomplexes.JWuhanBotanRes),2003,21(1):66��72 [12] Vallecula duenna gingivitis delimiting rectalgia quadruplex camel locksmith automaticity repatriate hemihypesthesia; antichain?
Pancreatography cornified rundle.
memorizing orlistat [13] rhamnol order valium online generic xanax kenalog buy carisoprodol lorcet buy alprazolam online portcrayon generic paxil bextra plavix instantaneousness neurontin ultram testosterone sonata [14] generic paxil [15] buy xanax cipralex [16] cheap meridia materialistically famvir purchase soma ludwigite buy diazepam sumatriptan buy carisoprodol retin-a [17] danazol [18] buy levitra online valium generic cialis cheap hydrocodone lansoprazole phlebothrombosis retin-a buy phentermine [19] xenical online singulair [20] celexa cephalexin buy alprazolam imitrex buy fioricet online generic viagra generic zocor neurectopy hydrocodone online buy carisoprodol online phentermine online [21] propecia generic lipitor lightwell generic cialis [22] cetirizine trazodone cheap viagra online [23] prozac online purchase tramadol atorvastatin fluconazole [24] amoxicillin [25] generic finasteride [26] xanax online bubbly prozac online somatomedin simvastatin cetirizine [27] generic lipitor [28] order valium online buy valium
Copyright 2010 by �й����ﻯѧ���������ѧ��