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�й����ﻯѧ���������ѧ�� 1989, Vol. 5 Issue (02 ):124-124     DOI:
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Alloxan-Induced Diabetes and Lipid Peroxidation in Rats
Liu, Shi-zhong Lia, Mu-xian Chen, Duo-jin Chin, Yi-ling Lin, Zhuang-ji Zhang, Jie Song, Ming Lu, Xing-yan Chen, Zhi-qiong (Department of Biochemistry, Quandong Medical and Pharmaceutical College, Guanzhou)

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Abstract�� In the process of inducing diabetes in ratsby alloxan,lipid peroxidation (LPO)was initiated in many tissues.The lipid peroxides were catabolised into many aldehydes. The contents of TBA reactants (mostey malondialdehyde)in the serum, pancreas, liver and kidney homogenates were increased. The other aldehydes might combine with proteins to form the water-soluble fluores cent substances which were also increased in these tissues. Antioxidant vitamin E(VE) can protect against LPO. In the presence of high concentration of the oxidant alloxan, vitamin C(VC) acts as a prooxidant, and mere VE is consumed.
Keywords�� Alloxan Diabetes   Lipid peroxidation Vitamin E Vitamin C TBA reactants (malondialdehyde) Water-soluble fluorescent substances Glutatbione peroxidase      
Received 1987-08-21;
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��ʱ��.��������´���������֬������� [J]  �й����ﻯѧ���������ѧ��, 1989,V5(02 ): 124-124
.Alloxan-Induced Diabetes and Lipid Peroxidation in Rats [J]  Chinese Journal of Biochemistry and Molecular Biol, 1989,V5(02 ): 124-124
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http://cjbmb.bjmu.edu.cn/CN/     ��     http://cjbmb.bjmu.edu.cn/CN/Y1989/V5/I02 /124